|
Phenylethyl is a structural skeleton found
in sympathomimetic amines that have important physiological
functions within the body as neurotransmitters in the central nervous
system and hormones in the blood circulation. Phenyl ketone structure is
found in keto alkaloids such as cathinone, a contributor of stimulant
effect. Phenyl ketone is a fuel in the brain. Propiophenone might be an
useful intermediate to prepare nervous system drugs (anxiolytic
and hypnotic drugs). Bupropion is an example which has propiophenone
moiety. It is a constituent of synthetic perfumes, flavouring agents, and
paints to stabilize other ingredients. Ketones can be made by the
oxidation of secondary alcohols and the destructive distillation of
certain salts of organic acids. In addition to as polar solvents, ketones
are important intermediates in the syntheses of organic compounds such as
alkoxides, hydroxyalkynes, imines, alcohols (primary, secondary as well
as tertiary), acetals, thioacetals, phosphine oxides, geminal diols,
hydrazones, organic sulfite and cyanohydrins.
|
|
